Overview | Notation | Analysis-specific normalization | $$c =\frac | RevMan-style sample-size scaling | RevMan-style inverse-standard-error scaling | Package-specific graphical rescaling | Symbol geometry and equal-area scaling | A controlled example | $$\sqrt | Using the sizing methods | Relation to the other sizing methods | $$w_ | $$w_ | $$q_ | $$q_ | Latent-class extension | Total sample-size scaling | Empirical Bayes precision scaling | $$\widetilde d_ | $$\widetilde d_ | Interpretation and limitations | Summary | \frac

How do I load the package? | Which model should I use? | Validation | How do I use the Reitsma model? | $$\begin | How do I get a summary plot of the Reitsma model? | How do I get a coupled forest plot? | How do I export results to RevMan? | How do I fit the Reitsma model using the custom TMB backend? | An example illustrating numerical behaviour near the boundary | How do I use the Rutter and Gatsonis model? | How do I get a summary plot of the Rutter and Gatsonis model? | How do I simplify the models via parameter constraints? | How do I use the Hoyer model? | Which distributions does dtametaTMB support? | Weibull distribution | Log-normal distribution | Log-logistic distribution | Random effects structure | Censoring mechanism | How do I compute sensitivities and specificities? | How do I interpret test direction? | In a nutshell | How do I fit the Hoyer model? | How do I get a summary plot of the Hoyer model? | How do I fit the Hoyer model to the FeNO dataset? | How does testdirection="less" work? | How does fitHoyer work internally? -- Optional advanced workflow | Step 1: How do we restructure the data set? | Step 2: How do we get initial values? | Step 3: How do we fit the model? | References

What are latent class models? | Which latent class models does dtametaTMB support? | What is conditional independence? | How do latent class models work? | How do we model disease prevalence? | $$\text{logit}(\pi_i) | How do we model the index test? (Reitsma version) | $$\text{logit}(Se_{i}) | $$\text{logit}(Sp_{i}) | How do we model the index test? (Rutter and Gatsonis version) | $$x_ | $$\eta_ | \left(\Theta+\theta_i | How do we model the reference test? | $$Se_R | $$Sp_R | How do we model the latent-class probabilities? | $$p_ | $$p_ | $$p_ | $$p_ | Model parameters (Reitsma version) | Model parameters (Rutter and Gatsonis version) | How does the model provide study-specific sensitivities/specificities? | How do we obtain starting values? | How do I fit the Reitsma latent class model? | How do I get a summary plot? | How do I get a coupled forest plot? | How do I fit the Rutter and Gatsonis latent class model? | How do I perform subgroup analyses? | Reitsma subgroup latent class model | Rutter and Gatsonis subgroup latent class model | How do I fit the Reitsma subgroup latent class model? | How do I apply these methods to the schuetz data set? | References

Validation | Dummy-coding vs. cell-means parameterization | How do we include covariates in the Reitsma model? | How do I get a summary plot of the Reitsma model? | How do I get a coupled forest plot? | How do I constrain parameters in the Reitsma model? | How can I compare constrainsens with the full model? | How do I allow for different subgroup-specific random-effects (co-)variances in the Reitsma model? | How do I fit the Reitsma subgroup model using the custom TMB backend? | How do we include covariates in the Rutter and Gatsonis model? | How do I perform a Rutter and Gatsonis meta-regression with a single categorical study-level covariate? | How do I get a summary plot of the Rutter and Gatsonis subgroup model? | How do I constrain parameters in the Rutter and Gatsonis subgroup model? | How do I use the general Rutter and Gatsonis regression function? | How do I compare models? | How do I get the log likelihood, the AIC, and the BIC of a model? | How do I perform a likelihood ratio test of the two models? | How do I replicate results from the Cochrane Handbook with respect to the schuetz data set? | What are the results for the full data set? | What are the results for the direct comparisons? | References